Title : Dexmedetomidine attenuates the toxicity of β‑amyloid on neurons and astrocytes by increasing BDNF production under the regulation of HDAC2 and HDAC5.

Pub. Date : 2019 Jan

PMID : 30483749






3 Functional Relationships(s)
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1 Dexmedetomidine attenuates the toxicity of beta-amyloid on neurons and astrocytes by increasing BDNF production under the regulation of HDAC2 and HDAC5. Dexmedetomidine brain-derived neurotrophic factor Rattus norvegicus
2 However, Dex reversed the Abeta-induced deacetylation of histone H3 and thus, increased BDNF production. Dexmedetomidine brain-derived neurotrophic factor Rattus norvegicus
3 These results suggested that the protective effect of Dex against Abeta is particularly relevant to BDNF. Dexmedetomidine brain-derived neurotrophic factor Rattus norvegicus