Pub. Date : 2019 Mar
PMID : 30470919
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cucurbitacin B induces mitochondrial-mediated apoptosis pathway in cholangiocarcinoma cells via suppressing focal adhesion kinase signaling. | cucurbitacin B | protein tyrosine kinase 2 | Homo sapiens |
| 2 | Further molecular analyses revealed that cucurbitacin B inhibited focal adhesion kinase (FAK), which is an important regulator of the apoptosis process, and its downstream pathway, PI3K/Akt. | cucurbitacin B | protein tyrosine kinase 2 | Homo sapiens |
| 3 | Further molecular analyses revealed that cucurbitacin B inhibited focal adhesion kinase (FAK), which is an important regulator of the apoptosis process, and its downstream pathway, PI3K/Akt. | cucurbitacin B | protein tyrosine kinase 2 | Homo sapiens |
| 4 | Taken together, cucurbitacin B induces an intrinsic mitochondrial apoptosis pathway in CCA cells partly through suppression of FAK-mediated oncogenic signaling. | cucurbitacin B | protein tyrosine kinase 2 | Homo sapiens |