Title : Sesquiterpene lactones from Ambrosia arborescens Mill. inhibit pro-inflammatory cytokine expression and modulate NF-κB signaling in human skin cells.

Pub. Date : 2018 Nov 15

PMID : 30466970






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 HYPOTHESIS/PURPOSE: The sesquiterpene lactones (SLs) coronopilin and damsin, which are major secondary metabolites of A. arborescens, have anti-inflammatory activity by attenuation of IL-6 and MCP-1 expression and inhibition of NF-kappaB in human dermal fibroblasts (HDFa) and human keratinocytes (HaCaT). Sodium dodecyl sulfate interleukin 6 Mus musculus