Title : Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-κB/ERK signaling pathway in Raw264.7 cells.

Pub. Date : 2018 Dec 1

PMID : 30466615






2 Functional Relationships(s)
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1 Icariin abrogates osteoclast formation through the regulation of the RANKL-mediated TRAF6/NF-kappaB/ERK signaling pathway in Raw264.7 cells. icariin tumor necrosis factor (ligand) superfamily, member 11 Mus musculus
2 We found that icariin inhibited RANKL-stimulated TRAF-6 expression, and subsequently suppressed the phosphorylation of ERK, but icariin did not show an effect on p38, JNK, and Akt activation. icariin tumor necrosis factor (ligand) superfamily, member 11 Mus musculus