Pub. Date : 2018
PMID : 30464525
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | Besides that, resveratrol treatment inhibited Akt/mTOR while p38-MAPK was activated in NSCLC cells in a dose-dependent manner. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Conclusion: Taken together, our findings suggest that resveratrol inhibited proliferation but induced apoptosis and autophagy via inhibiting Akt/mTOR and activating p38-MAPK pathway. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |