Pub. Date : 2018 Nov 19
PMID : 30456861
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dexmedetomidine alleviates cerebral ischemia-reperfusion injury in rats via inhibition of hypoxia-inducible factor-1alpha. | Dexmedetomidine | hypoxia inducible factor 1 subunit alpha | Rattus norvegicus |
| 2 | Thus, we aimed to study the role and mechanism of Dex in cerebral I/R injury by inhibiting hypoxia-inducible factor-1alpha (HIF-1alpha) and apoptosis. | Dexmedetomidine | hypoxia inducible factor 1 subunit alpha | Rattus norvegicus |
| 3 | Thus, we aimed to study the role and mechanism of Dex in cerebral I/R injury by inhibiting hypoxia-inducible factor-1alpha (HIF-1alpha) and apoptosis. | Dexmedetomidine | hypoxia inducible factor 1 subunit alpha | Rattus norvegicus |
| 4 | Furthermore, activation of HIF-1alpha expression blocks the inhibitory effect of Dex on neuronal apoptosis in I/R rats. | Dexmedetomidine | hypoxia inducible factor 1 subunit alpha | Rattus norvegicus |
| 5 | Dex may inhibit the neuronal apoptosis of I/R rats by inhibiting the HIF-1alpha pathway and then improve the cerebral I/R injury in rats. | Dexmedetomidine | hypoxia inducible factor 1 subunit alpha | Rattus norvegicus |