Title : Differences in PD-L1 expression on tumor and immune cells between lung metastases and corresponding primary tumors.

Pub. Date : 2018 Dec

PMID : 30449485






3 Functional Relationships(s)
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1 The percentages of PD-L1-positive TCs and ICs in lung metastases and the primary tumor were classified into five categories (0: <1%; 1: 1%-4%; 2: 5%-9%; 3: 10%-49%; and 4: >=50%). 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens
2 Discrepancies in PD-L1 expression on TCs and ICs between lung metastases and primary lesions were observed in 5 (11.4%, kappa = 0.23) and 9 (20.5%, kappa = 0.11) of the 44 cases, respectively. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens
3 PD-L1 expression on ICs was higher in lung metastases than paired primary tumors (p = 0.026), although the percentage of PD-L1-positive TCs was not significantly different between lung metastases and primary tumors (p = 0.767). 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide CD274 molecule Homo sapiens