Pub. Date : 2019 Feb
PMID : 30443985
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polyphenols and Tryptophan Metabolites Activate the Aryl Hydrocarbon Receptor in an in vitro Model of Colonic Fermentation. | Tryptophan | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Specific dietary phytochemicals, such as luteolin, as well as specific microbial metabolites of tryptophan are ligands of the aryl hydrocarbon receptor (AhR), which plays a role in immunity and homeostasis of the gut barrier. | Tryptophan | aryl hydrocarbon receptor | Homo sapiens |
| 3 | Specific dietary phytochemicals, such as luteolin, as well as specific microbial metabolites of tryptophan are ligands of the aryl hydrocarbon receptor (AhR), which plays a role in immunity and homeostasis of the gut barrier. | Tryptophan | aryl hydrocarbon receptor | Homo sapiens |
| 4 | The greatest AhR activity is due to microbiota-derived metabolites of tryptophan, particularly in the descending colon. | Tryptophan | aryl hydrocarbon receptor | Homo sapiens |
| 5 | Tryptophan metabolism by the microbiota in the colon contributes substantially to the pool of lumen metabolites that can activate the AhR. | Tryptophan | aryl hydrocarbon receptor | Homo sapiens |