Title : Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice.

Pub. Date : 2018 Nov 27

PMID : 30429322






2 Functional Relationships(s)
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1 Expression of the candidate target gene Ppara is decreased in white adipose tissue but not in the liver of mimic-treated (MIMIC) mice, and this is accompanied by increased circulating free fatty acids and hypertriglyceridemia. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus
2 Importantly, simultaneously reducing free fatty acid plasma levels in MIMIC mice with either the lipolysis inhibitor acipimox or the PPARalpha agonist fenofibrate partially protects against these metabolic alterations. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus