Pub. Date : 2019 Jan 1
PMID : 30423706
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeting graphene quantum dots to epidermal growth factor receptor for delivery of cisplatin and cellular imaging. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 2 | The targeted CDDP-loaded nanocarriers ((CDDP)GQDs-scFvB10) exhibited significantly higher toxicity on MDA-MB-231 cells compared to non-targeted ones suggesting their efficient uptake through EGFR. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 3 | The targeted CDDP-loaded nanocarriers ((CDDP)GQDs-scFvB10) exhibited significantly higher toxicity on MDA-MB-231 cells compared to non-targeted ones suggesting their efficient uptake through EGFR. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 4 | In contrast, cells with saturated EGFR showed lower uptake and cytotoxic effect of (CDDP)GQDs-scFvB10, demonstrating selectivity of the nanocarriers towards EGFR-overexpressing cells. | Cisplatin | epidermal growth factor receptor | Homo sapiens |
| 5 | In contrast, cells with saturated EGFR showed lower uptake and cytotoxic effect of (CDDP)GQDs-scFvB10, demonstrating selectivity of the nanocarriers towards EGFR-overexpressing cells. | Cisplatin | epidermal growth factor receptor | Homo sapiens |