Title : Physical blood-brain barrier disruption induced by focused ultrasound does not overcome the transporter-mediated efflux of erlotinib.

Pub. Date : 2018 Dec 28

PMID : 30415015






1 Functional Relationships(s)
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Protein Name
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1 Inhibition of ABCB1 and ABCG2 at the mouse BBB improved the BBB permeation of erlotinib but could not be achieved in humans. Erlotinib Hydrochloride ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus