Pub. Date : 2018 Nov 8
PMID : 30409185
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: We demonstrated that a high concentration of unconjugated bilirubin induced cell death in SHED via the mitochondrial pathway, and this was associated with the suppression of AKT and extracellular signal-related kinase 1 and 2 (ERK1/2) signal pathways and activation of the nuclear factor kappa B (NF-kappaB) signal pathway. | Bilirubin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | RESULTS: We demonstrated that a high concentration of unconjugated bilirubin induced cell death in SHED via the mitochondrial pathway, and this was associated with the suppression of AKT and extracellular signal-related kinase 1 and 2 (ERK1/2) signal pathways and activation of the nuclear factor kappa B (NF-kappaB) signal pathway. | Bilirubin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | We then demonstrated that pamidronate decreased the bilirubin-induced cell death in SHED via the altered AKT, ERK1/2, and NF-kappaB signal pathways and recovered the bilirubin-impaired dentinogenic function of SHED. | Bilirubin | nuclear factor kappa B subunit 1 | Homo sapiens |