Title : Elevation of plasma levels of fluorinated pyrimidines by guanosine 5'-monophosphate.

Pub. Date : 1987

PMID : 3040286






1 Functional Relationships(s)
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1 After administration of FdCyd plus GMP, the plasma levels of FdCyd, 5-fluoro-2"-deoxyuridine, which is converted from FdCyd by cytidine deaminase, and FUra were 2-, 6-, and 7-fold higher, respectively, than those after FdCyd alone 30 min after treatment. 5-fluoro-2'-deoxyuridine cytidine deaminase Homo sapiens