Pub. Date : 2018 Oct
PMID : 30393482
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study the effect of IP6 on autophagy-mediated death by modulating the mTOR pathway in HT-29 colon cancer cells was studied. | Phytic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | mTOR pathway regulates autophagy and incubation with IP6 to HT-29 cells showed decreased expression of p-70S6Kinase, 4-EBP-1 in a time-dependent manner. | Phytic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Conclusions: Our results clearly indicate that IP6 induces autophagy by inhibiting the Akt/mTOR pathway. | Phytic Acid | mechanistic target of rapamycin kinase | Homo sapiens |