Title : 3-Dehydroandrographolide protects against lipopolysaccharide-induced inflammation through the cholinergic anti-inflammatory pathway.

Pub. Date : 2018 Dec

PMID : 30391477






5 Functional Relationships(s)
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1 Furthermore, 3-DA increased alpha7nAchR expression level and bound with alpha7nAchR. 3-da cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Furthermore, 3-DA increased alpha7nAchR expression level and bound with alpha7nAchR. 3-da cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 More importantly, the anti-inflammatory effects of 3-DA were counteracted in the presence of alpha7nAchR siRNA or methyllycaconitine (MLA, a alpha7nAchR specific inhibitor), suggesting that alpha7nAchR is a potential target in the anti-inflammatory effects of 3-DA. 3-da cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
4 More importantly, the anti-inflammatory effects of 3-DA were counteracted in the presence of alpha7nAchR siRNA or methyllycaconitine (MLA, a alpha7nAchR specific inhibitor), suggesting that alpha7nAchR is a potential target in the anti-inflammatory effects of 3-DA. 3-da cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
5 More importantly, the anti-inflammatory effects of 3-DA were counteracted in the presence of alpha7nAchR siRNA or methyllycaconitine (MLA, a alpha7nAchR specific inhibitor), suggesting that alpha7nAchR is a potential target in the anti-inflammatory effects of 3-DA. 3-da cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus