Title : Xanthatin induces apoptosis by activating endoplasmic reticulum stress in hepatoma cells.

Pub. Date : 2019 Jan 15

PMID : 30389633






2 Functional Relationships(s)
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1 More importantly, both xanthatin and tunicamycin, an endoplasmic reticulum stress (ERS) inducing compound, increased the levels of CHOP and cleaved-caspase-3 in HepG2 cells, but their effects were significantly abolished by siRNA-mediated knockdown of CHOP. Tunicamycin DNA damage inducible transcript 3 Homo sapiens
2 More importantly, both xanthatin and tunicamycin, an endoplasmic reticulum stress (ERS) inducing compound, increased the levels of CHOP and cleaved-caspase-3 in HepG2 cells, but their effects were significantly abolished by siRNA-mediated knockdown of CHOP. Tunicamycin DNA damage inducible transcript 3 Homo sapiens