Pub. Date : 2019 May
PMID : 30370612
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hepcidin and iron regulatory proteins coordinately regulate ferroportin 1 expression in the brain of mice. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 2 | Ferroportin 1 (FPN1) is the currently only known iron exporter on the cell membrane. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 3 | Ferroportin 1 (FPN1) is the currently only known iron exporter on the cell membrane. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 4 | It has been indicated that the regulation of FPN1 in response to the alteration of iron level mainly involves two processes, posttranscriptional repression by iron regulatory proteins (IRPs) and posttranslational degradation by hepcidin, the major iron-sensing hormone. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 5 | It has been indicated that the regulation of FPN1 in response to the alteration of iron level mainly involves two processes, posttranscriptional repression by iron regulatory proteins (IRPs) and posttranslational degradation by hepcidin, the major iron-sensing hormone. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 6 | It has been indicated that the regulation of FPN1 in response to the alteration of iron level mainly involves two processes, posttranscriptional repression by iron regulatory proteins (IRPs) and posttranslational degradation by hepcidin, the major iron-sensing hormone. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 7 | Further investigation disclosed that the compromised hepcidin-FPN1 regulation in IRP2-/- cells was directly dependent on the existence of iron-responsive element (IRE) in FPN1 messenger RNA. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |
| 8 | Further investigation disclosed that the compromised hepcidin-FPN1 regulation in IRP2-/- cells was directly dependent on the existence of iron-responsive element (IRE) in FPN1 messenger RNA. | Iron | solute carrier family 40 (iron-regulated transporter), member 1 | Mus musculus |