Title : Gamma-secretase inhibitor suppressed Notch1 intracellular domain combination with p65 and resulted in the inhibition of the NF-κB signaling pathway induced by IL-1β and TNF-α in nucleus pulposus cells.

Pub. Date : 2018 Oct 26

PMID : 30367520






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Western blot revealed that DAPT inhibited p65 phosphorylation and acetylation, and the p65 and p50 levels in the nucleus decreased. dapt RELA proto-oncogene, NF-kB subunit Homo sapiens