Title : Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Pub. Date : 2018 Oct 18

PMID : 30337562






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LSN3213128 is a potent (16 nM) anti-folate inhibitor of AICARFT and selective relative to TS, SHMT1, MTHFD1, MTHFD2 and MTHFD2L. lsn3213128 serine hydroxymethyltransferase 1 Homo sapiens