Title : Metformin inhibits mTOR-HIF-1α axis and profibrogenic and inflammatory biomarkers in thioacetamide-induced hepatic tissue alterations.

Pub. Date : 2019 Jun

PMID : 30334569






2 Functional Relationships(s)
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1 Metformin inhibits mTOR-HIF-1alpha axis and profibrogenic and inflammatory biomarkers in thioacetamide-induced hepatic tissue alterations. Metformin hypoxia inducible factor 1 subunit alpha Homo sapiens
2 Therefore, we tested whether metformin can protect against liver injuries including fibrosis induced by TAA possibly via the downregulation of mTOR-HIF-1alpha axis and profibrogenic and inflammatory biomarkers. Metformin hypoxia inducible factor 1 subunit alpha Homo sapiens