Pub. Date : 2018 Dec 21
PMID : 30333251
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celastrol significantly inhibited ERK1/2 phosphorylation in cell lines and xenograft tumors. | celastrol | mitogen-activated protein kinase 3 | Homo sapiens |
| 2 | In summary, we unraveled the anti-CRC function of Celastrol and confirmed for the first time that it inhibited the ERK1/2 pathway through binding to Shoc2. | celastrol | mitogen-activated protein kinase 3 | Homo sapiens |