Title : Thermodynamic destabilization and aggregation propensity as the mechanism behind the association of apoE3 mutants and lipoprotein glomerulopathy.

Pub. Date : 2018 Dec

PMID : 30309894






1 Functional Relationships(s)
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1 We previously showed that three mutants based on apoE3 sequence, in which an arginine was substituted by proline, are thermodynamically destabilized and aggregation-prone. Arginine apolipoprotein E Homo sapiens