Title : Beta 2-adrenoceptor induced increase of plasma insulin levels in man: evidence of direct and indirect B-cell stimulation and liver effects.

Pub. Date : 1986 Nov

PMID : 3030608






5 Functional Relationships(s)
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1 20 min after terbutaline injection, plasma levels of C-peptide were 0.98 +/- 0.26 nmol/l and of insulin were 0.21 +/- 0.05 nmol/l. Terbutaline insulin Homo sapiens
2 Calculations of the minute to minute increase of plasma levels of C-peptide and insulin during the 20 min after terbutaline injection, revealed that plasma insulin increased during the first 2 min by 59 +/- 8% of the increase of plasma C-peptide, and during the third and fourth min by 44 +/- 12% of the increase of plasma C-peptide; the difference being the liver extraction of insulin. Terbutaline insulin Homo sapiens
3 Calculations of the minute to minute increase of plasma levels of C-peptide and insulin during the 20 min after terbutaline injection, revealed that plasma insulin increased during the first 2 min by 59 +/- 8% of the increase of plasma C-peptide, and during the third and fourth min by 44 +/- 12% of the increase of plasma C-peptide; the difference being the liver extraction of insulin. Terbutaline insulin Homo sapiens
4 In contrast, during min 4-10 after terbutaline injection, plasma insulin levels increased more than did plasma C-peptide levels, indicating that terbutaline inhibits the liver extraction of insulin. Terbutaline insulin Homo sapiens
5 In contrast, during min 4-10 after terbutaline injection, plasma insulin levels increased more than did plasma C-peptide levels, indicating that terbutaline inhibits the liver extraction of insulin. Terbutaline insulin Homo sapiens