Title : Increasing the distance between two monomers of topoisomerase IIβ under the action of antitumor agent 4β-sulfur-(benzimidazole) 4'-demethylepipodophyllotoxin.

Pub. Date : 2018 Oct 8

PMID : 30297860






1 Functional Relationships(s)
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1 The mechanism of the Top2s poisons such as etoposide (VP-16) was reported as stabilizing the Top2-DNA complex and engendering permanent DNA breakage. Etoposide host cell factor C1 Homo sapiens