Title : Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension.

Pub. Date : 2018 Oct 3

PMID : 30282928






2 Functional Relationships(s)
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1 The serum concentrations of angiotensin Ang 1-8 (Ang II), Ang 1-5, Ang 1-7, Ang 1-10, Ang 2-8, and Ang 3-8 were decreased in the L-NAME group and ivabradine did not modify them. NG-Nitroarginine Methyl Ester angiotensinogen Rattus norvegicus
2 The serum concentration of aldosterone and the aldosterone/Ang II ratio were enhanced by L-NAME and ivabradine reduced these changes. NG-Nitroarginine Methyl Ester angiotensinogen Rattus norvegicus