Title : Efficacy of metformin in mediating cellular uptake and inducing apoptosis activity of doxorubicin.

Pub. Date : 2018 Nov

PMID : 30266241






1 Functional Relationships(s)
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1 These findings suggest that the combined treatment of metformin with DOX potentiates the anticancer efficacy of DOX in DU145 cells via inhibiting ABCB1 function, cell cycle arrest at G1/S transition and apoptosis induction. Metformin ATP binding cassette subfamily B member 1 Homo sapiens