Pub. Date : 2018 Dec
PMID : 30248327
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene. | Calcium | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Some ligands may also trigger more rapid nongenomic responses through AhR, including calcium signaling (Ca2+). | Calcium | aryl hydrocarbon receptor | Homo sapiens |
| 3 | Use of pharmacological inhibitors and Ca2+-free medium indicated that the pyrene-induced AhR nongenomic [Ca2+]i increase was initiated by Ca2+-release from intracellular stores followed by a later phase of extracellular Ca2+-influx, consistent with store operated calcium entry (SOCE). | Calcium | aryl hydrocarbon receptor | Homo sapiens |