Pub. Date : 2018 Sep
PMID : 30247813
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously found that preconstriction of intact, isolated mouse mesenteric arteries with phenylephrine also caused increased Ser1179 and decreased Thr495 eNOS phosphorylation, and sequential treatment with the vasodilatory agonist acetylcholine did not cause any further change in phosphorylation at these sites, despite producing vasodilation. | Phenylephrine | nitric oxide synthase 3, endothelial cell | Mus musculus |
| 2 | In separate arteries, preconstriction with phenylephrine (10-5 mol/L) resulted in increased eNOS phosphorylation at Ser1179 (P < 0.05) and decreased phosphorylation at Thr495, but subsequent flow at 60 muL/min for 5 or 15 min did not cause further changes in phosphorylation, despite causing dilation. | Phenylephrine | nitric oxide synthase 3, endothelial cell | Mus musculus |