Pub. Date : 2018 Jul 27
PMID : 30240640
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFbeta-TRCP E3 Ubiquitin Ligase. | Serine | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | Here we report that Ser 422 of IRS-1 is phosphorylated by mTORC1 and required for IRS-1 degradation induced by prolonged IGF stimulation. | Serine | CREB regulated transcription coactivator 1 | Mus musculus |