Pub. Date : 2018 Sep
PMID : 30229580
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Lack of S1P induced by sphingosine kinase inhibitor (SphKi) treatment caused beta-cell dysfunction and apoptosis, with repression of mitochondrial function shown by decreases in cellular adenosine triphosphate content, the oxygen consumption rate, the expression of oxidative phosphorylation complexes, the mitochondrial membrane potential, and the expression of key regulators of mitochondrial dynamics (mitochondrial dynamin-like GTPase [OPA1] and mitofusin 1 [MFN1]). | Adenosine Triphosphate | sphingosine-1-phosphate receptor 1 | Mus musculus |