Pub. Date : 2018 Oct
PMID : 30219715
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In individual HLMs with variable CYP2D6 activities, a significant correlation was observed between celecoxib hydroxylation and CYP2D6-selective dextromethorphan O-demethylation when CYP2C9 and CYP3A4 activities were suppressed (r = 0.97, P < 0.0001). | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | In individual HLMs with variable CYP2D6 activities, a significant correlation was observed between celecoxib hydroxylation and CYP2D6-selective dextromethorphan O-demethylation when CYP2C9 and CYP3A4 activities were suppressed (r = 0.97, P < 0.0001). | Dextromethorphan | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |