Title : Cardioprotective cytokine interleukin-33 is up-regulated by statins in human cardiac tissue.

Pub. Date : 2018 Dec

PMID : 30216659






1 Functional Relationships(s)
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1 The lipophilic fluvastatin, simvastatin, atorvastatin, and lovastatin as well as the nitrogenous BPs alendronate and ibandronate, but not hydrophilic pravastatin increased IL-33 mRNA and intracellular IL-33 protein levels in both human adult cardiac myocytes (HACM) and fibroblasts (HACF). Atorvastatin interleukin 33 Homo sapiens