Title : Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia.

Pub. Date : 2019 Apr

PMID : 30214012






1 Functional Relationships(s)
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1 We now report the pre-clinical anti-leukemic efficacy of a novel BCL-2 inhibitor S55746, which demonstrates synergistic pro-apoptotic activity in combination with the MCL1 inhibitor S63845. S63845 BCL2 apoptosis regulator Homo sapiens