Pub. Date : 2018 Sep 11
PMID : 30208561
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells. | Tacrolimus | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | Tacrolimus (FK506) has been identified as an MRP1 regulator in differentiated glioblastoma (GBM) cells (non-GSCs); however, the effect of FK506 on GSCs is currently unknown. | Tacrolimus | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 3 | Tacrolimus (FK506) has been identified as an MRP1 regulator in differentiated glioblastoma (GBM) cells (non-GSCs); however, the effect of FK506 on GSCs is currently unknown. | Tacrolimus | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 4 | The objective of the following research is to evaluate the effect of FK506 on the MRP1-related chemo-resistant phenotype of GSCs. | Tacrolimus | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 5 | We conclude that FK506 confers a chemo-sensitive phenotype to MRP1-drug substrate in GSCs. | Tacrolimus | ATP binding cassette subfamily C member 1 | Homo sapiens |