Pub. Date : 2019 Feb
PMID : 30207798
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Iron overload by transferrin receptor protein 1 regulation plays an important role in palmitate-induced insulin resistance in human skeletal muscle cells. | Iron | insulin | Homo sapiens |
| 2 | The association between iron disturbances and insulin resistance has recently begun to receive a lot of attention. | Iron | insulin | Homo sapiens |
| 3 | We investigated the molecular mechanism underlying iron dysregulation in PA-induced insulin resistance. | Iron | insulin | Homo sapiens |
| 4 | The iron chelator deferoxamine dramatically inhibited PA-induced insulin resistance, and iron donors impaired insulin sensitivity by activating JNK. | Iron | insulin | Homo sapiens |
| 5 | Knockdown of tfR1 and iron-responsive element-binding proteins 2 prevented PA-induced iron uptake and insulin resistance. | Iron | insulin | Homo sapiens |
| 6 | Iron overload may play a critical role in PA-induced insulin resistance. | Iron | insulin | Homo sapiens |
| 7 | Blocking iron overload may thus be a useful strategy for preventing insulin resistance and diabetes.-Cui, R., Choi, S.-E., Kim, T. H., Lee, H. J., Lee, S. J., Kang, Y., Jeon, J. Y., Kim, H. J., Lee, K.-W. Iron overload by transferrin receptor protein 1 regulation plays an important role in palmitate-induced insulin resistance in human skeletal muscle cells. | Iron | insulin | Homo sapiens |
| 8 | Blocking iron overload may thus be a useful strategy for preventing insulin resistance and diabetes.-Cui, R., Choi, S.-E., Kim, T. H., Lee, H. J., Lee, S. J., Kang, Y., Jeon, J. Y., Kim, H. J., Lee, K.-W. Iron overload by transferrin receptor protein 1 regulation plays an important role in palmitate-induced insulin resistance in human skeletal muscle cells. | Iron | insulin | Homo sapiens |