Pub. Date : 2018 Sep 11
PMID : 30206977
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A unified mitochondria mechanistic target of rapamycin acyl-coenzyme A dehydrogenase 10 signal relay modulation for metformin growth inhibition in human immortalized keratinocytes cells. | Metformin | acyl-CoA dehydrogenase family member 10 | Homo sapiens |
| 2 | In the current study, we found that after metformin treatment the proliferation of human immortalized keratinocytes (HaCaT) was significantly inhibited, while cell apoptosis was increased in a dose-dependent manner, accompanied with enhanced protein expression of acyl-coenzyme A dehydrogenase 10 (ACAD10). | Metformin | acyl-CoA dehydrogenase family member 10 | Homo sapiens |
| 3 | In the current study, we found that after metformin treatment the proliferation of human immortalized keratinocytes (HaCaT) was significantly inhibited, while cell apoptosis was increased in a dose-dependent manner, accompanied with enhanced protein expression of acyl-coenzyme A dehydrogenase 10 (ACAD10). | Metformin | acyl-CoA dehydrogenase family member 10 | Homo sapiens |
| 4 | This study showed that the metformin treatment inhibited HaCaT cells proliferation and promoted apoptosis by affecting the mitochondrial-mTORC1 signaling and elevated the ACAD10 expression. | Metformin | acyl-CoA dehydrogenase family member 10 | Homo sapiens |