PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30206977-0 2018 A unified mitochondria mechanistic target of rapamycin acyl-coenzyme A dehydrogenase 10 signal relay modulation for metformin growth inhibition in human immortalized keratinocytes cells. Metformin 116-125 acyl-CoA dehydrogenase family member 10 Homo sapiens 55-87 30206977-2 2018 In the current study, we found that after metformin treatment the proliferation of human immortalized keratinocytes (HaCaT) was significantly inhibited, while cell apoptosis was increased in a dose-dependent manner, accompanied with enhanced protein expression of acyl-coenzyme A dehydrogenase 10 (ACAD10). Metformin 42-51 acyl-CoA dehydrogenase family member 10 Homo sapiens 264-296 30206977-2 2018 In the current study, we found that after metformin treatment the proliferation of human immortalized keratinocytes (HaCaT) was significantly inhibited, while cell apoptosis was increased in a dose-dependent manner, accompanied with enhanced protein expression of acyl-coenzyme A dehydrogenase 10 (ACAD10). Metformin 42-51 acyl-CoA dehydrogenase family member 10 Homo sapiens 298-304 30206977-6 2018 This study showed that the metformin treatment inhibited HaCaT cells proliferation and promoted apoptosis by affecting the mitochondrial-mTORC1 signaling and elevated the ACAD10 expression. Metformin 27-36 acyl-CoA dehydrogenase family member 10 Homo sapiens 171-177