Title : Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.

Pub. Date : 2019 Jan 8

PMID : 30197302






1 Functional Relationships(s)
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1 Here we describe that the Leu metabolite acetyl-coenzyme A (AcCoA) positively regulates mTORC1 activity by EP300-mediated acetylation of the mTORC1 regulator, Raptor, at K1097. Leucine E1A binding protein p300 Mus musculus