Title : Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.

Pub. Date : 2018 Sep 9

PMID : 30196308






2 Functional Relationships(s)
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1 RESULTS Oxymatrine and Notch signaling pathway inhibitor DAPT could attenuated TGF-beta1 induced the capacity of proliferation and migration increased in cardiac fibroblasts, as well as the secretion of collagen and hydroxyproline colorimetric content in medium. dapt transforming growth factor, beta 1 Rattus norvegicus
2 TGF-beta1 induced the biomarker alpha-SMA of fibroblast-to-myofibroblast transformation (FMT), which was inhibited by oxymatrine and DAPT. dapt transforming growth factor, beta 1 Rattus norvegicus