Title : A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia.

Pub. Date : 2018 Dec

PMID : 30185627






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Induced myeloid leukemia cell differentiation protein (MCL1), an antiapoptotic BCL2 family member, is commonly upregulated in AML cells and is often a primary mode of resistance to treatment with the BCL2 inhibitor venetoclax. venetoclax MCL1 apoptosis regulator, BCL2 family member Homo sapiens