Title : Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells.

Pub. Date : 1986 Sep 25

PMID : 3017977






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A functional human EGF-receptor is expressed on the surface of heterologous CHO cells with the following properties: it exhibits typical high affinity (10%; Kd = 3 X 10(-10) M) and low affinity (90%; Kd = 3 X 10(-9) M) binding sites for 125I-EGF; it is expressed as a polypeptide of 170,000 molecular weight with intrinsic protein tyrosine kinase activity. cho epidermal growth factor receptor Homo sapiens