Title : The regulation of intracellular pH in monkey kidney epithelial cells (BSC-1). Roles of Na+/H+ antiport, Na+-HCO3(-)-(NaCO3-) symport, and Cl-/HCO3- exchange.

Pub. Date : 1986 Sep 15

PMID : 3017962






3 Functional Relationships(s)
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1 When HCO3- was lowered from 46 to 10 mM at constant pCO2 (5%), pHi dropped by a DIDS-sensitive mechanism. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid glucose-6-phosphate isomerase Homo sapiens
2 In bicarbonate saline, two other mechanisms effect pHi regulation: a DIDS-sensitive Na+-HCO3- symport, which contributes to cytoplasmic alkalinization, and a DIDS-sensitive Cl-/HCO3- exchange, which is apparently independent of Na+. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid glucose-6-phosphate isomerase Homo sapiens
3 In bicarbonate saline, two other mechanisms effect pHi regulation: a DIDS-sensitive Na+-HCO3- symport, which contributes to cytoplasmic alkalinization, and a DIDS-sensitive Cl-/HCO3- exchange, which is apparently independent of Na+. 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid glucose-6-phosphate isomerase Homo sapiens