Title : Desuppression of TGF-β signaling via nuclear c-Abl-mediated phosphorylation of TIF1γ/TRIM33 at Tyr-524, -610, and -1048.

Pub. Date : 2019 Jan

PMID : 30177833






1 Functional Relationships(s)
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1 Replacement of the three tyrosine residues Tyr-524, -610, and -1048 with phenylalanine (3YF) inhibits c-Abl-mediated phosphorylation of TIF1gamma and enhances TIF1gamma"s association with Smad3. Phenylalanine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens