Title : p38 MAPK Facilitates Crosstalk Between Endoplasmic Reticulum Stress and IL-6 Release in the Intervertebral Disc.

Pub. Date : 2018

PMID : 30174670






2 Functional Relationships(s)
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1 Both inhibition of p38 MAPK by SB203580 (10 microM) and knockdown of ER stress effector CCAAT-enhancer-binding protein homologous protein (CHOP) reduced gene and protein expression of IL-6 in Tg-treated cells. Thapsigargin DNA damage inducible transcript 3 Homo sapiens
2 Both inhibition of p38 MAPK by SB203580 (10 microM) and knockdown of ER stress effector CCAAT-enhancer-binding protein homologous protein (CHOP) reduced gene and protein expression of IL-6 in Tg-treated cells. Thapsigargin DNA damage inducible transcript 3 Homo sapiens