Title : Efficient Industrial Synthesis of the MDM2 Antagonist Idasanutlin via a Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition.

Pub. Date : 2018 Aug 22

PMID : 30158012






2 Functional Relationships(s)
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1 Efficient Industrial Synthesis of the MDM2 Antagonist Idasanutlin via a Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition. RG7388 MDM2 proto-oncogene Homo sapiens
2 A concise asymmetric synthesis has been developed to prepare idasanutlin, a small molecule MDM2 antagonist. RG7388 MDM2 proto-oncogene Homo sapiens