Title : Sodium-Calcium Exchanger Can Account for Regenerative Ca2+ Entry in Thin Astrocyte Processes.

Pub. Date : 2018

PMID : 30154700






3 Functional Relationships(s)
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1 However, cytosolic sodium and calcium are also allosteric regulators of the NCX, thus adding kinetic constraints on the NCX-mediated fluxes and providing for complexity of the system dynamics. Sodium solute carrier family 8 member A1 Homo sapiens
2 However, cytosolic sodium and calcium are also allosteric regulators of the NCX, thus adding kinetic constraints on the NCX-mediated fluxes and providing for complexity of the system dynamics. Sodium solute carrier family 8 member A1 Homo sapiens
3 Our modeling indicates that the calcium-dependent activation and also calcium-dependent escape from the sodium-mediated inactive state of the NCX in astrocytes can form a positive feedback loop and lead to regenerative calcium influx. Sodium solute carrier family 8 member A1 Homo sapiens