PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30154700-4 2018 However, cytosolic sodium and calcium are also allosteric regulators of the NCX, thus adding kinetic constraints on the NCX-mediated fluxes and providing for complexity of the system dynamics. Sodium 19-25 solute carrier family 8 member A1 Homo sapiens 76-79 30154700-4 2018 However, cytosolic sodium and calcium are also allosteric regulators of the NCX, thus adding kinetic constraints on the NCX-mediated fluxes and providing for complexity of the system dynamics. Sodium 19-25 solute carrier family 8 member A1 Homo sapiens 120-123 30154700-5 2018 Our modeling indicates that the calcium-dependent activation and also calcium-dependent escape from the sodium-mediated inactive state of the NCX in astrocytes can form a positive feedback loop and lead to regenerative calcium influx. Sodium 104-110 solute carrier family 8 member A1 Homo sapiens 142-145