Title : Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuit.

Pub. Date : 2018

PMID : 30153269






1 Functional Relationships(s)
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1 These data suggest that the HO-1-derived metabolites, CO and bilirubin, elevate astrocytic mitochondrial function via a HIF-1alpha/ERRalpha circuit coupled with L-type Ca2+ channel activation and PGC-1alpha-mediated oxygen consumption. Oxygen heme oxygenase 1 Homo sapiens