Title : Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel.

Pub. Date : 2018 Oct

PMID : 30138624






1 Functional Relationships(s)
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1 The substrates and inhibitors of hOCT1 are structurally and physiochemically diverse and include some widely prescribed drugs (metformin and imatinib), vitamins (thiamine), and neurotransmitters (serotonin). Metformin solute carrier family 22 member 1 Homo sapiens