Pub. Date : 2019 Feb 1
PMID : 30137220
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we first examined whether rosiglitazone, an agonist of the peroxisome proliferator-activated receptor-gamma (PPARgamma), protects the human trophoblast from oxidative injury by regulating key antioxidant proteins, catalase (CAT) and the superoxide dismutases (SOD1 and SOD2). | Rosiglitazone | superoxide dismutase 2 | Homo sapiens |
| 2 | Treatment with rosiglitazone dose-dependently upregulated anti-oxidative CAT and SOD2, and rescued hypoxic injury in first trimester villous explants and JEG-3 cells, strongly suggesting the involvement of the PPARgamma in regulating their expressions. | Rosiglitazone | superoxide dismutase 2 | Homo sapiens |